Xeno 450 Ivermectin Spot-on for Small Animals (pack of 6)

XENO® 450 Spot-on solution is a simple and effective spot-on for the prevention and control of common internal and external parasites on small mammals such as rabbits, guinea pigs and ferrets, and birds.
Brand Xeno
Manufacturer Dechra
Species Guinea Pig, Ferret, Rabbit, Bird
Prescription Type AVM-GSL (OTC licensed veterinary medicine)
In stock

What is Xeno 450 spot-on and who is it for?


XENO® 450 Spot-on solution is a simple and effective way to keep your small pet reliably parasite free.

Applied to the skin, XENO® 450 is absorbed into the body and is particularly effective against the parasites which commonly cause ear disease in the rabbit and ferret, and the mites that cause skin disease in guinea pigs, and rabbits. This includes the mite that causes mange in guinea pigs and the condition known as walking dandruff in rabbits.

It is also effective against many of the parasites which cause skin and feather problems in birds.

The active substance in XENO® 450 Spot-on solution is ivermectin, a substance known as an endectocide because it kills parasites that cause infestation inside the body (endoparasites) as well as those living outside the body, on the skin (ectoparasites). Ivermectin is used in many species for the control of mites, roundworms and lice.

XENO® 450 Spot-on solution is intended for use on rabbits, guinea pigs and ferrets over 1.2 kg body weight, and birds over 666 g body weight.

Cartons containing 6 polypropylene tubes, each of 450 ?g ivermectin.

What is in Xeno 450 spot-on?


1 pipette contains:

Active substance: Ivermectin 450 μg

How do I use Xeno 450 spot-on?


Species ( μg = microgram ) Body weight (g) Amount to apply
Rabbits, guinea pigs and ferrets (200-400 μg/kg) 1.2 kg to 2.25 kg 1 pipette
2.25 kg to 4.5 kg 2 pipettes
4.5 kg to 6.75 kg 3 pipettes
Birds (225 μg/kg) Over 666 grams 1 drop per 100g bodyweight

It is very important to weigh your animal accurately as overdosing can be harmful. Your veterinary practice can help to weigh your pet.
Each pipette contains 450 μg ivermectin. Each pipette contains approximately 20 drops. Each drop will deliver approximately 22.5 μg ivermectin

How to apply:

  1. Holding the pipette firmly in one hand, twist off the cap.
  2. Mammals: Using the dosage table, apply the correct number of drops or pipettes onto the skin on the back of the neck and down the spine.
    Birds: Apply 1 drop (22.5 μg) per 100 g body weight under the feathers onto the skin of the back between the wings.
  3. For routine prevention of common ectoparasites this dose should be repeated monthly. For the treatment of an existing infestation, repeat doses are required two weeks and four weeks after the initial application.

Special precautions for storage: Keep out of the sight and reach of children. Do not store above 25?C. Protect from light. Discard remaining contents of any opened pipettes immediately following use. Dispose of waste materials in accordance with local requirements.


  • Do not overdose.
  • Avoid use in or around the eyes.
  • Do not use on animals other than those indicated. Serious reactions, including deaths, have been reported in dogs (especially Collies, Old English Sheepdogs and related breeds), tortoises and turtles treated with products containing the active substance. This product is toxic to chelonians. Do not use in tortoises, turtles or related species.
  • For pet animals only. Do not use in animals intended for human consumption. Do not eat eggs from treated birds.

Special precautions to be taken by the person administering the product to animals:

  • Wash hands after use. 

Adverse reactions:

Occasionally, central nervous system disorders, lethargy, inappetance, local irritation and/or hypersensitivity reactions may be observed. These signs may be more common in young animals. Should such a reaction occur, discontinue use and seek veterinary advice. If you notice any serious effects or other effects not mentioned in this data sheet, please inform your veterinary surgeon.

Is there any further advice I should know about Xeno 450 spot-on?


Xeno Spot-On is not effective against ringworm. Ringworm is a skin disease which can be passed on from your pet to humans. If you think your pet may have ringworm, you should consult a veterinary surgeon.

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