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Simparica 5mg Chewable Tablets for Tiny Dogs 1.3 - 2.5kg (pack of 3)

Simparica Chewable Tablets are an antiparastic tablet designed for dogs. To be given for the treatment of flea or tick infestations in dogs. Suitable for tiny dogs (1.5-2.5kg).
Brand Simparica
Manufacturer Zoetis
Species Dog
Prescription Type POM-V (Written prescription required)
£21.79
In stock
Reference
Med-1809460

Prescription Medicine

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Name: Simparica 5mg Chewable Tablets for Tiny Dogs 1.3 - 2.5kg (pack of 3)

Description: Simparica Chewable Tablets are an antiparastic tablet designed for dogs. To be given for the treatment of flea or tick infestations in dogs. Suitable for tiny dogs (1.5-2.5kg).

Description

Simparica Chewable Tablets are an antiparastic tablet designed for dogs. To be given for the treatment of flea or tick infestations in dogs. Suitable for tiny dogs (1.5-2.5kg).

 

For the treatment of flea infestations (Ctenocephalides felis and Ctenocephalides canis) in dogs. Simparica has immediate and persistent flea killing activity against new infestations for at least 5 weeks. Simparica can be used as part of a treatment strategy for the control of Flea Allergy Dermatitis (FAD).

For the treatment of tick infestations (Dermacentor reticulatus, Ixodes hexagonus, Ixodes ricinus and Rhipicephalus sanguineus). Simparica has immediate and persistent tick killing activity for at least 5 weeks.

For the treatment of sarcoptic mange (Sarcoptes scabiei). Fleas and ticks must attach to the host and commence feeding in order to be exposed to the active substance.

 

Prescription only medicine.
Simparica Chewable Tablets are only available with a prescription from your veterinary surgeon.
To check the most up to date information about this product, please read its Summary of Product Characteristics (SPC) below:
http://www.vmd.defra.gov.uk/ProductInformationDatabase/Default.aspx

Properties

Sarolaner is an acaricide and insecticide belonging to the isoxazoline family. The primary target of action of sarolaner in insects and acarines is functional blockade of ligand-gated chloride channels (GABA-receptors and glutamate-receptors). Sarolaner blocks GABA- and glutamate-gated chloride channels in the central nervous system of insects and acarines.

For fleas, the onset of efficacy is within 8 hours of attachment during the 28 day period after product administration. For ticks (I. ricinus), the onset of efficacy is within 12 hours of attachment during the 28 day period after product administration. Ticks on the animal prior to administration are killed within 24 hours.

 

Simparica kills newly emerged fleas on the dog before they can lay eggs and therefore it prevents environmental flea contamination in areas to which the dog has access.
In addition, in laboratory studies, sarolaner was shown to be active against other tick species such as Dermacentor variabilis, Ixodes scapularis, Amblyomma americanum, Amblyomma maculatum as well as the mite species Demodex canis and Otodectes cynotis.

During clinical field trials, no interactions between Simparica chewable tablets for dogs and routinely used veterinary medicinal products were observed.

In laboratory safety studies, no interactions were observed when sarolaner was co-administered with milbemycin oxime, moxidectin and pyrantel pamoate. (In these studies efficacy was not investigated).

Sarolaner is highly bound to plasma proteins and might compete with other highly bound drugs such as non-steroidal anti-inflammatory drugs (NSAIDs) and the cumarin derivative warfarin.

 

Packaging

Pack containing 3 tablets.

Composition

Active substance
Sarolaner 5 mg

Directions

Simparica is a prescription product and must be applied according to the instructions by your veterinary surgeon.

Please read the product leaflet thoroughly before applying to your pet.

Further advice

Contra-indications, warnings, etc

  • Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
  • Parasites need to start feeding on the host to become exposed to sarolaner; therefore, the transmission of infectious parasite-borne diseases cannot be excluded.
  • In the absence of available data, treatment of puppies less than 8 weeks of age and/or dogs less than 1.3 kg bodyweight should be based on a benefit-risk assessment by the responsible veterinarian.
  • The safety of Simparica has not been established during pregnancy and lactation or in animals intended for breeding. Laboratory studies in rats and rabbits have not produced any evidence of any teratogenic effects. Use only according to the benefit/risk assessment by the responsible veterinarian.
  • Simparica has been administered orally to 8 week old Beagle puppies at doses of 0, 1, 3, and 5 times the maximum dose of 4 mg/kg at 28 day intervals for 10 doses. No adverse effects were observed at the maximum dose of 4 mg/kg. In the overdose groups, transient and self-limiting neurological signs were observed in some animals: mild tremors at 3 times the maximum dose and convulsions at 5 times the maximum dose. All dogs recovered without treatment.
  • Sarolaner is well tolerated in Collies with a deficient multidrug-resistance-protein 1 (MDR1 -/-) following single oral administration at 5 times the recommended dose. No treatment-related clinical signs were observed.

User warnings

  • Wash hands after handling the product.
  • The accidental ingestion of the product may potentially result in adverse effects, such as transient excitatory neurological signs.
  • To prevent children from accessing the product, only one chewable tablet at a time should be removed from the blister pack and only when required.The blister pack should then be returned into the carton immediately after use and the carton should be stored out of the sight and reach of children.
  • In case of accidental ingestion, seek medical advice immediately and show the package leaflet or label to the physician.

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