Malaseb Shampoo for Cats & Dogs 250ml

Malaseb is a shampoo used for the treatment of dermatitis in dogs, and as an aid in the treatment of ringworm in cats.
Brand Malaseb
Manufacturer Dechra
Species Cat, Dog
Prescription Type POM-V (Written prescription required)
Out of stock
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What is Malaseb and who is it for?


Malaseb is a shampoo for the treatment and control of seborrhoeic dermatitis associated with Malassezia pachydermatis and Staphylococcus intermedius in dogs.

It is also used as an aid in the treatment of ringworm due to Microsporum canis in conjunction with griseofulvin in cats.


This is a Prescription only medicine (POM-V).

Malaseb is only available with a prescription from your veterinary surgeon.

To check the most up to date information about this product, please read its Summary of Product Characteristics (SPC). It can be viewed here.

What are the active ingredients is Malaseb?


Chlorhexidine digluconate is a Bisbiguanide antimicrobial agent against Gram-positive and Gram-negative bacteria. It is both bactericidal and bacteriostatic depending on the concentration used.

Growth inhibition is achieved by a direct effect on ATP-ase so interfering with the energy transport mechanisms. The bactericidal effect of chlorhexidine results from coagulation of the bacterial cell contents.

Chlorhexidine digluconate is incorporated in the product for its activity against Staphylococcus intermedius. Typical MIC values found in clinical Staphylococcus intermedius isolates are 2.0 mg/l (2005). Staphylococcus intermedius resistance to chlorhexidine has not been reported.

High concentrations of chlorhexidine digluconate are achieved in the hair coat and on the skin for the 10 minute period following shampooing. These concentrations are well in excess of the MICs for Staphylococcus intermedius. Chlorhexidine digluconate is poorly absorbed from the gastrointestinal tract on ingestion. There is little or no percutaneous absorption. In humans, it has been shown that 26% remains on the skin at 29 hours after application.


Miconazole nitrate is an imidazole antifungal agent with activity against yeasts such as Malassezia pachydermatis.

It is both fungicidal and fungistatic depending on the concentration used. Miconazole inhibits ergosterol incorporation into cell membranes so increasing concentrations of cytotoxic hydrogen peroxide within the fungal cell wall.

Miconazole nitrate has been incorporated in the product for its activity against Malassezia pachydermatis. Typical MIC values found in clinical Malassezia pachydermatis isolates are 0.5-4.0 mg/l (2003/5). Malassezia pachydermatis resistance to miconazole has not been reported.

High concentrations of miconazole nitrate are achieved in the hair coat and on the skin for the 10 minute period following shampooing. These concentrations are well in excess of the MICs for Malassezia pachydermatis.

Miconazole nitrate is poorly absorbed from the skin and gastrointestinal tract.


Chlorhexidine and miconazole in combination:

In vitro studies have demonstrated synergistic activity against Microsporum canis between chlorhexidine and miconazole.

250ml bottle

What is in Malaseb?


Clear to slightly unclear, light yellow to light brown liquid shampoo.


Each ml contains: 

Active substances:

Chlorhexidine digluconate 20 mg (equivalent to chlorhexidine 11.26 mg)

Miconazole nitrate 20 mg (equivalent to miconazole 17.37 mg)



Methylchloroisothiazolinone 0.0075 mg

Methylisothiazolinone 0.0025 mg

Sodium Benzoate 1.25mg

How do I use Malaseb?

Malaseb is a prescription product and must be used according to the instructions of your veterinary surgeon.

Please read the product leaflet thoroughly before administering to your pet.

Is there any further advice I should know about Malaseb?




Do not use in case of hypersensitivity to the active substances or to any of the excipients.


Special warnings for each target species


Dogs and cats: In order to prevent reoccurrence of the infection, appropriate control methods should be employed in the animal’s environment (e.g. cleaning and disinfection of kennels, beds).

Cats: Malaseb shampoo should only be used in conjunction with griseofulvin when treating for ringworm. Shampooing cats may initially increase the recovery of M. canis by brush culture techniques. Both field and experimental studies have shown that environmental contamination with M. canis can be eliminated or reduced by the use of Malaseb shampoo twice weekly. In these studies, griseofulvin was administered continuously throughout the treatment period and both clinical improvement was enhanced and environmental contamination reduced compared to the use of griseofulvin alone.


Special precautions for use


Official, national and regional antimicrobial polices should be taken into account when the product is used.


Special precautions for use in animals


For external use only.

In case of accidental contact with eyes, rinse with plenty of water.

Do not allow the animal to lick itself during shampooing and rinsing, or before it is dried. Take care to avoid the animal inhaling the product or getting it into the nose or mouth during shampooing.

Puppies and kittens should not come into contact with nursing females after treatment until the coat has dried.

Special precautions to be taken by the person administering the product to animals

People with known hypersensitivity to chlorhexidine, miconazole or any of the excipients should avoid contact with the veterinary medicinal product.

This product can cause eye irritation. Avoid contact with the eyes. In case of accidental contact with eyes, rinse with plenty of water. If irritation persists consult your doctor.

Avoid excessive handling and stroking of treated animals immediately following treatment.

Ringworm in the cat is infectious to humans and so it is advisable to wear gloves and have arms covered during clipping and shampooing of infected cats.

When shampooing a cat, in order to avoid prolonged contact with the shampoo, wash and dry hands gently. Do not scrub.


Adverse reactions


Exceptionally, a dog with atopy or a cat with allergic skin disease may develop a pruritic and/or erythematous reaction after treatment.

In very rare circumstances, dogs and cats may develop a skin reaction (itching, redness) after treatment.


Use during pregnancy and lactation


Pregnancy: Malaseb shampoo in conjunction with griseofulvin should not be used in pregnant cats as griseofulvin is contraindicated in pregnancy.

Lactation: Please see Special precautions for use in animals.

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