Bravecto 112.5mg Chewable Tablet for Toy Dogs 2 - 4.5kg (single tablet)
| Brand | Bravecto |
| Manufacturer | Intervet |
| Species | Dog |
| Prescription Type | POM-V (Written prescription required) |
Description
Bravecto Chewable Tablets are an antiparasitic tablet designed for dogs. To be given for the management of flea or tick infestations in dogs. A single dose can provide 12 weeks of protection from fleas and most types of ticks. Suitable for extra small dogs (2 - 4.5kg).
Indications for use:
For the treatment of tick and flea infestations in dogs
This veterinary medicinal product is a systemic insecticide and acaricide that provides:
- immediate and persistent flea (Ctenocephalides felis) killing activity for 12 weeks,
- immediate and persistent tick killing activity for 12 weeks for Ixodes ricinus, Dermacentor reticulatus and D. variabilis,
- immediate and persistent tick killing activity for 8 weeks for Rhipicephalus sanguineus.
Fleas and ticks must attach to the host and commence feeding in order to be exposed to the active substance.
The onset of effect is within 8 hours of attachment for fleas (C. felis) and 12 hours of attachment for ticks (I. ricinus).
The product can be used as part of a treatment strategy for the control of flea allergy dermatitis (FAD).
This is Prescription only medicine (POM-V)
Bravecto Chewable Tablets are only available with a prescription from your veterinary surgeon.
To check the most up to date information about this product, please read its Summary of Product Characteristics (SPC) below:
http://www.vmd.defra.gov.uk/ProductInformationDatabase/Default.aspx
Properties
Fluralaner is an acaricide and insecticide. It is efficacious against ticks (Ixodes spp., Dermacentor spp. and Rhipicephalus sanguineus) and fleas (Ctenocephalides spp.) on the dog. It has a high potency against ticks and fleas by exposure via feeding, i.e. it is systemically active on target parasites.Fluralaner is a potent inhibitor of parts of the arthropod nervous system by acting antagonistically on ligand-gated chloride channels (GABA-receptor and glutamate-receptor). In molecular on-target studies on insect GABA receptors of flea and fly, fluralaner is not affected by dieldrin resistance.
In in vitro bio-assays, fluralaner is not affected by proven field resistances against amidines (tick), organophosphates (tick, mite), cyclodienes (tick, flea, fly), macrocyclic lactones (sea lice), phenylpyrazoles (tick, flea), benzophenyl ureas (tick), pyrethroids (tick, mite) and carbamates (mite).
The product contributes towards the control of the environmental flea populations in areas to which treated dogs have access.
Newly emerged fleas on a dog are killed before viable eggs are produced. An in vitro study also demonstrated that very low concentrations of fluralaner stop the production of viable eggs by fleas.The flea life cycle is broken due to the rapid onset of action and long lasting efficacy against adult fleas on the animal and the absence of viable egg production.
Packaging
Single tabletComposition
Active substances:
Fluralaner 112.5 mg
Directions
Bravecto is a prescription product and must be applied according to the instructions by your veterinary surgeon.
Please read the product leaflet thoroughly before applying to your pet.
Legal Notice
Marketing Authorisation Holder
Intervet International BV, The Netherlands
Marketing Authorisation Number
EU/2/13/158/001
Further advice
Contra-indications
- Do not use in case of hypersensitivity to the active substance or to any of the excipients.
Special warnings for each target species
- Parasites need to start feeding on the host to become exposed to fluralaner; therefore the risk of the transmission of parasite borne diseases cannot be excluded.
Special precautions for use in animals
- In the absence of available data, the veterinary medicinal product should not be used on puppies less than 8 weeks old and /or dogs weighing less than 2 kg.
- The product should not be administered at intervals shorter than 8 weeks as the safety for shorter intervals has not been tested.
Operator warnings
- Keep the product in the original packaging until use, in order to prevent children from getting direct access to the product.
- Do not eat, drink or smoke while handling the product.
- Wash hands thoroughly with soap and water immediately after use of the product.
Adverse reactions
- Commonly observed adverse reactions in clinical trials (1.6% of treated dogs) were mild and transient gastrointestinal effects such as diarrhoea, vomiting, inappetence, and drooling.
- The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals displaying adverse reaction(s) during the course of one treatment)
- common (more than 1 but less than 10 animals in 100 animals)
- uncommon (more than 1 but less than 10 animals in 1,000 animals)
- rare (more than 1 but less than 10 animals in 10,000 animals)
- very rare (less than 1 animal in 10,000 animals, including isolated reports).
Use during pregnancy, lactation or lay
- The safety of the veterinary medicinal product in breeding, pregnant and lactating dogs has been demonstrated. Can be used in breeding, pregnant and lactating dogs.
Interactions
- None known.
Fluralaner is highly bound to plasma proteins and might compete with other highly bound drugs such as non-steroidal anti-inflammatory drugs (NSAIDs) and the cumarin derivative warfarin. Incubation of fluralaner in the presence of carprofen or warfarin in dog plasma at maximum expected plasma concentrations did not reduce the protein binding of fluralaner, carprofen or warfarin.
During clinical field testing, no interactions between Bravecto chewable tablets for dogs and routinely used veterinary medicinal products were observed.
